Zambia has a population of approximately 17 million people with a health system of about 2700 health facilities. The HIV prevalence rate is about 11.6%. In responding to the care and treatment needs for PLHIV, with the support of PEPFAR, Zambia has scaled up treatment services to about 1,000,000 individuals representing about 80% of HIV infected individuals in need of treatment since 2004. In ensuring that the health system continues to be capable and resilient in providing quality care and treatment services to people in need, among other interventions CDC Zambia through PEPFAR has invested in the development of SmartCare, an Electronic Health Record (EHR) system, to support patient management and improve clinical decisions.